Thursday, February 27, 2020

A genetically modified virus is a virus that has been altered or generated using biotechnology methods

7-26-2017  Lentiviral vectors are virus particles that can be used as a vaccine to stimulate the immune system to fight against specific pathogens. The vectors are derived from HIV, rendered non-pathogenic, and then engineered to carry genetic material into the body's immune cells; the genes program the cells to fight specific pathogens. New research from the laboratory of David Baltimore, president emeritus and the Robert Andrews Millikan Professor of Biology, shows that additional materials acquired during the vector's formation—namely, proteins and human genomic DNA—play an important role in activating the immune system. Understanding how lentiviral vectors interact with the immune system is critical to improving vaccines so as to maximize the immune response, and to understanding infectious processes occurring in natural pathogens.  https://medicalxpress.com/news/2017-07-genetically-viruses-effective-vaccines.html
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  2-3-20   Viruses mutate all the time, but most changes are synonymous or “silent”, having little effect on the way the virus behaves. Others, known as nonsynonymous substitutions, can alter biological traits, allowing them to adapt to different environments.
  Two nonsynonymous changes took place in the viral strains isolated from the family, according to a new study by Professor Cui Jie and colleagues at the Institut Pasteur of Shanghai—in the paper published in the journal National Science Review on January 29.  https://www.scmp.com/news/china/science/article/3048772/striking-coronavirus-mutations-found-within-one-family-cluster
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 A genetically modified virus is a virus that has been altered or generated using biotechnology methods and remains capable of infection.  Genetic modification involves the directed insertion, deletion, artificial synthesis or change of nucleotide bases in viral genomes.

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 11-17-2016    The genetically engineered virus as the cause of humanity’s downfall, although equally ironic, is perhaps scarier than the prospect of nuclear war because it is more of an unknown. What is it? As the name implies, it is a virus that has been created or modified at a genetic level. Scientists have started to toy with these viruses to treat other human illnesses, such as cancer. For example, researchers in a lab could create a virus that targets and kills cancer cells, curing patients without chemotherapy. But there are possible applications for just about any condition, including alcoholism. Smithsonian Magazine reported that a genetically engineered virus could reduce the urge to drink by introducing a certain gene into neurons that control behavior of an addicted brain, and then manipulating them into encouraging or discouraging the problem behavior….
  …some experts have been warning us about the dangers of these genetically modified viruses and the risk of an infectious outbreak for at least a decade. One article in the Journal of Toxicology and Environmental Health targets viruses whose DNA has been modified as well as vaccines that use genetically engineered viruses. They “possess significant unpredictability and a number of inherent harmful potential hazards,” even to people who are not the patient and to other species, the article says. And when the engineered viruses in vaccines reproduce with their naturally occurring counterparts, they may “possess totally unpredictable characteristics with regard to host preferences and disease-causing potentials.”
  Aside from engineered viruses possibly creating offspring in our bodies in unpredictable ways that ultimately make them stronger and impervious to our current medical treatments, one way these modified or engineered viruses could start infecting us and spread like wildfire could be a containment issue in a laboratory setting, which is not unheard of — the Centers for Disease Control and Prevention had a scare a few years ago when employees were at risk of exposure to anthrax.
  The genetically engineered viruses that could start an outbreak in a lab that spreads to the rest of humanity are already out there.  In a Wisconsin lab, Gizmodo has reported, one scientist created a strain of the feared H1N1 flu, commonly referred to as “swine flu” several years ago, that “can completely escape the human immune system” and its antibodies — making us all “unable to resist an outbreak.”  https://www.medicaldaily.com/genetically-engineered-virus-dangers-why-does-stephen-hawking-think-it-will-404595
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10-5-2001  Experts fear that the genetic revolution, which helped map the Human Genome, may provide terrorists with far more deadly weapons, that could bring about diseases that would be even more difficult to treat than anthrax or smallpox.
  "Advances in genomics have greatly increased the possibilities of mixing and matching traits from different microorganisms," says Dr. Ketan Desai, bioterrorism expert and author of Germs of War.
This mixing and matching, also known as recombinant technology, can be used, for example, to take a gene that makes a deadly toxin from one strain of bacteria and introduce it into other bacterial strains.
Dangerous pathogens or infectious agents can be made more deadly, and relatively benign agents can become major public health problems….
   "In my opinion, this is not fanciful and there is good reason for concern," says Dr. David Yandell, Director of the Vermont Comprehensive Cancer Center. The expertise and technology to create lethal new strains of viruses and bacteria are available at almost any university in the United States and abroad.  "I don't think that the public realizes fully that this is not rocket science," says Yandell.  https://abcnews.go.com/Health/story?id=117204&page=1
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(2) Articles in Nature journal (2015): Engineered bat virus stirs debate over risky research
(3) Wuhan biolab experts worked in USA (Univ. North Carolina) & Canada
(Winnipeg) and brought that research home to Wuhan
(4/5) Wuhan Lab ( Prof. Zhengli Shi and Xingyi Ge ) did the genetic engineering for Ralph Baric at University of North Carolina
(6) The spike glycoprotein of 2019-nCoV contains a cleavage absent in CoV  - showing that it was engineered rather than evolved
(7) Asians show a similar ACE2 expression to other races; virus will affect all races
(9) Professor Shi Zhengli is deputy-director of the P4 lab at Wuhan Institute of Virology  https://www.gazetawarszawska.com/index.php/pugnae/4558-wuhan-biolab
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  Ralph Baric’s research specializes in coronaviruses and emerging infections like Zika virus. In a recent interview he discusses whether the world is prepared for the next superbug outbreak....Most of the research in the Baric Lab uses coronaviruses as models to study the genetics of RNA virus transcription, replication, persistence and cross-species transmission. Dr. Baric also has used alphavirus vaccine vectors to develop novel candidate vaccines. https://sph.unc.edu/adv_profile/ralph-s-baric-phd/
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alpha virus replicon vectors are being developed as a platform vaccine technology for numerous viral, bacterial, protozoan and tumour antigens where they have been shown to be efficient inducers of both humoral and T cell responses.

Alphavirus vectors and vaccination. - NCBI

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by Y Yang - ‎2015 - ‎Cited by 51 - ‎Related articles
Jun 10, 2015 - ... of Middle East Respiratory Syndrome Coronavirus. Yang Yang, Chang Liu, Lanying Du, Shibo Jiang, Zhengli ShiRalph S. Baric, Fang Li.
by Y Wan - ‎2020 - ‎Cited by 34
Jan 29, 2020 - Yushun Wan 1,*, Jian Shang 1,*, Rachel Graham 2, Ralph S. Baric 2, Fang ... Zheng-Li Shi PZ, Xing-Lou Yang, Xian-Guang Wang, Ben Hu, Lei ...
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Wednesday, February 26, 2020

"irresponsible and unreasonable" reliance on China

As of Feb. 25, the Shandong government stated that there were a total of 755 infections in the province. But the internal document (covertly passed to Epoch Times) showed that 1,992 people had tested positive for the virus via nucleic acid testing as of Feb. 23.     https://techstartups.com/2020/02/26/leaked-internal-document-reveals-coronavirus-infections-52-times-higher-reported-figures-chinas-shandong-province/ in China
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the virus outbreak has highlighted an "irresponsible and unreasonable" reliance on China, according to French finance minister Bruno Le Maire  https://www.aljazeera.com/news/2020/02/china-coronavirus-outbreak-latest-updates-200225003320810.html
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France is now reporting its 18th case of coronavirus, the country's Health Minister said in a news conference in Paris.  https://www.cnn.com/asia/live-news/coronavirus-outbreak-02-26-20-intl-hnk/index.html
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S. Korea cases shoot up again--my numbers may not turn out to be for last 24 hours; 284/977= 29% increase.   -r
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9:50 p.m. London time 2-26-20  Iran has no plans to quarantine any cities and towns
https://www.bbc.com/news/world-middle-east-51651454


Monday, February 24, 2020

the genetic tampering "science"

  Scientists at the University of California San Diego implanted the dengue immune proteins, called antibodies, into female mosquitoes.
  Antibodies are created naturally by the body and are what enables the immune system to destroy bacteria and viruses by itself without medical help.  But someone must become infected with, or exposed to, an illness before the body is able to develop them, which is risky with such a deadly disease.
  The researchers found putting human dengue antibodies into mosquitoes stopped the disease spreading among the insects.  And by engineering the genes of the insects to make sure those with the antibodies inside them were successful breeders, researchers said it would be possible to make this immunity spread through the wild population of the insects.  

Professor Omar Akbari, who led the study, said:  "Once the female mosquito takes in blood, the antibody is activated and expressed--that's the trigger.  The antibody is able to hinder the replication of the virus and prevent its dissemination throughout the mosquito, which then prevents its transmission to humans. It's a powerful approach.  It is fascinating that we now can transfer genes from the human immune system to confer immunity to mosquitoes."…
  Professor Alphey cautioned that a small mutation in the dengue virus would make it resistant to the antibody which the scientists used, thus able to spread again. 
"It’s just one antibody so you expect resistance to evolve fairly quickly.  This example only has one antibody in it.  So a small change in the virus would lead to resistance to that one antibody.”     https://www.dailymail.co.uk/health/article-7894859/Scientists-engineer-dengue-resistant-mosquitoes.html


  Emailoakbari@ucsd.edu
Phone858-246-0640
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9-20-19  In fact the genes that were passed on weren't the tweaked genes that were designed to kill and tag the mosquitoes but rather genes from the strains in Cuba and Mexico, according to Science magazine.  The researchers also noted that this mixing of genes might have led to a "more robust population," perhaps one that would be better able to resist insecticides or transmit diseases, Science magazine reported. 
  That suggestion has prompted a backlash from the company.  "We're not surprised by the results, but what we are surprised by are the speculations that the authors have made," Nathan Rose, head of scientific and regulatory affairs at Oxitec, told Science magazine.   https://www.livescience.com/genetically-modified-mosquitoes-create-hybrids.html
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  We could tear down billions of years of mother nature’s evolutionary patterns and replace that with, what, lab jelly?  -r, mt. shasta

Sunday, February 23, 2020

African drug trade; 10 flights daily S. Korea to Hong Kong

9-22-19   Precursor chemicals, which get diverted for the illicit manufacture of synthetic opioids or heroin, are sneaked into African countries from China and India….
Drug traffickers such as the Akasha brothers would use the chemicals to secretly mass produce synthetic drugs at laboratories they had set up in South Africa, Zimbabwe, Kenya, Tanzania, Congo, Burundi and Mozambique….
Hamisi Massa, the head of Kenya’s Anti-Narcotics Unit, said China and India were the main sources of precursor chemicals used to illicitly make drugs and especially of Mandrax, abba and ephedrine. 
Once the drugs were made, they would be moved by private yachts and through unpoliced ports, according to security experts in Kenya.
Analysts say a lack of regulatory oversight has created favourable conditions for the mass production and exportation of synthetic opioids and other chemicals between the Asian countries and Africa….
“Unlike China, India does not have the controls and as a result, you have many pharmaceutical companies producing vast amounts of drugs that get diverted into the black market,” Franklin said.  “As you walk into a chemist here in Nairobi, you can buy a tramadol for US$1 a tablet.”

This action coincided with the sentencing in New York of Kenyan drug kingpin Baktash Akasha to 25 years in prison. Baktash’s brother, Ibrahim, who has pleaded guilty to charges of trafficking drugs to the United States, is to be sentenced in November.
Documents related to the Akasha brothers’ cases, filed in a district court in New York state, give a rare glimpse into how Asian countries such as China, India, Pakistan, Afghanistan and Iran may be fuelling the drug-abuse crisis on the Kenyan coast and in other African cities such as Lagos in Nigeria, and Cape Town, Johannesburg and Pretoria in South Africa.
Cocaine from South American countries such as Colombia and Bolivia is trafficked through Africa, and especially via East, West and North Africa, en route to lucrative markets in Europe.
But trade is not as prominent in cocaine as in heroin, according to security experts that track narcotics trafficking trends.
Hamisi Massa, the head of Kenya’s Anti-Narcotics Unit, said China and India were the main sources of precursor chemicals used to illicitly make drugs and especially of Mandrax, abba and ephedrine. 
Drug traffickers such as the Akasha brothers would use the chemicals to secretly mass produce synthetic drugs at laboratories they had set up in South Africa, Zimbabwe, Kenya, Tanzania, Congo, Burundi and Mozambique.
Once the drugs were made, they would be moved by private yachts and through unpoliced ports, according to security experts in Kenya.
Analysts say a lack of regulatory oversight has created favourable conditions for the mass production and exportation of synthetic opioids and other chemicals between the Asian countries and Africa….
Illicit labs in China ship the substances to foreign drug markets, especially those in Africa, for synthetic drug production….
Kenyan-based Security Advisory Services consultant Andrew Franklin said India was a huge source of tramadol – a form of opioid – that had spread all over Nigeria and was readily available over the counter in Kenya.
He said most precursors were used to make fentanyl, a synthetic heroin. Franklin, a former US Marine, said that although South Africa had very strict drug control laws, heroin use was high.
South Africa also had many ports and an advanced transport network covering most of Southern and Central Africa that made distributing the drugs easy, Franklin said.
But India may be fuelling the problem more.  “Unlike China, India does not have the controls and as a result, you have many pharmaceutical companies producing vast amounts of drugs that get diverted into the black market,” Franklin said.  “As you walk into a chemist here in Nairobi, you can buy a tramadol for US$1 a tablet
FulHis view is supported by Peter Gastrow, a senior adviser to the Global Initiative Against Transnational Organised Crime.  In India, Gastrow said, there was evidence that the country remained an essential source for the importation of precursor chemicals such as ephedrine, which is used to make methamphetamine, and methaqualone, a synthetic drug that is a central nervous system depressant. …Between 20 and 40 tonnes of heroin are trafficked through East Africa annually and there are indications the amount may be higher, according to Gastrow….
“Many law enforcement officers, judges, and border control officers have been weak and compromised through bribery and corruption,” Gastrow said.  “Political leadership [in Africa] on this issue has been weak.”   https://www.scmp.com/news/china/society/article/3027771/how-china-
and-other-asian-countries-are-fuelling-african-drug
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-Daegu, S. Korea

2-23-20   More than 10 flights a day connect Hong Kong and Incheon Airport in Seoul, according to Airport Authority figures.https://www.scmp.com/news/asia/east-asia/article/3051952/grave-coronavirus-situation-south-korean-city-daegu-mayor 

Saturday, February 22, 2020

Mixing and matching of genes is called recombination.

11-20-2008    Usually only one kind of virus infects a cell at any one time. Sometimes, though, two different kinds of virus can infect the same cell. This can sometimes result in a new virus made up of parts of the other two. But this only happens in very special cases.
  One such example was the Spanish flu. This disease spread worldwide right after World War I and killed upwards of 25 million people. The virus that caused the Spanish flu didn't exist before 1918. Experts think that it was a mix of human and bird flu viruses.
  Most likely someone was infected by both a bird and a human flu virus. The bird flu probably picked up some parts from the human virus that made it easier to spread and harder for the body to fight off.  But this kind of thing can't happen with the cold virus and Ebola. To be able to do this kind of mixing and matching, the viruses need to have very similar genetic material. And the cold virus and Ebola do not.
  Mixing and matching of genes is called recombination.  It can only happen between two pieces of DNA or RNA that have sections that are very similar. This is so the two pieces of genetic material can line up with each other and swap at these points….
The instructions for making new viruses are contained in a virus' genes. Each kind of virus has a different set of genes arranged in a different way.  What this means is that when two very different viruses recombine, the new virus will have a jumble of genes. Some genes needed to hijack a cell might go missing. Or those needed to make the outside of the virus might go missing.
  Or there might be duplicates of genes so that a mix of two shell proteins gets made. Or any number of other possibilities. The end result will almost certainly be something that can't do much of anything. And certainly not be a killer cold/Ebola virus!  While this is pretty much impossible in nature, it might be possible in a lab….
  In the past few years scientists have been able to create life (sort of). For example, at the beginning of 2008 scientists made a bacteria's DNA from scratch. Then they stuck it into a bacterium. The bacterium now used this new DNA as its instruction manual. Voila, life.
  Scientists have also created viruses from scratch. Because they are so simple, this is even easier than making a bacterium.
  Scientists had to stitch together 580,000 DNA letters in the right order to make a bacteria.  An Ebola virus only takes 19,000. And a cold virus 7,200!

  So scientists can pretty easily make an Ebola virus or a cold virus in the lab. But combining them into a supervirus is a whole different story.  By
Julia Oh, Stanford University     https://genetics.thetech.org/ask/ask290

Friday, February 21, 2020

Dear Pres. Trump: Who did you say was a loser?

David Enrich, financial editor for the NY Times, said the newspaper's estimate that major companies received tens of billions of dollars in additional tax breaks thanks to the Treasury Department is "conservative."
"The cumulative effect," said Enrich, "is that a tax law already disproportionately benefiting the richest of the rich has become an even greater windfall for the world's largest companies and their shareholders" (due to new tremendous extra perks).......
  
"the $4,000 annual boost to average incomes that the White House Council of Economic Advisers promised to working families because of the [Tax Cuts and Jobs Act] did not—and will not—happen."
https://www.commondreams.org/news/2019/12/30/trump-granting-lobbyist-demands-quietly-handed-billions-more-tax-breaks-huge 
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2-21-20  But the minute Richard Grenel, new acting director of national intelligence, went public about his homosexual domestic partnership he became a Marxist change agent, his very presence in public life an argument that a homosexual "orientation" is equivalent to normal sexuality. (Who in American history has ever wanted that goal? It wasn't the conservatives!)
  When Grenell did that he crossed the line from expecting reasonable tolerance from our genuinely magnanimous live-and-let-life society to demanding public acceptance. And in taking that step he also implicitly endorsed the progressive strategy of celebrating his "out" lifestyle as social progress, forcibly integrating it into society, and punishing those who object.  https://www.wnd.com/2020/02/richard-grenell-homosexual-trojan-horse/
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"Rick has represented our Country exceedingly well and I look forward to working with him," Trump wrote on Twitter on February 19 https://www.rferl.org/a/trump-ambassador-germany-kosovo-serbia-envoygrenell-intelligence-director/30444592.html
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2-21-20  Richard Grenell is the first openly gay person to hold a Cabinet-level position.  https://thehill.com/changing-america/respect/diversity-inclusion/484026-trump-names-the-first-openly-gay-person-to-a
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cancel out all ignorance and every false testimony

  Therefore let the great circle of our oneness and our love cancel out all division, all misunderstanding, all ignorance and every false testimony as in the case of the blind men and the elephant--all giving varied reports of the same spectacle but never arriving at the point of reality which is the heart:  heart perspective!…Behold, I make all things new by the flame of the heart, by the vision of the heart, by the wisdom of the heart that is the endless stream of the endless Source….
  Beloved ones, the reward for love is great.  But those who deserve it often do not receive it because they are the ones who are the busy ones or the fighters—driving, working, serving.  And therefore let us pause together.  Let us be still then in these lower vehicles and let us feel the chakras shining as the seven Elohim, shining as the Sun and the stars!…
let us not allow our ways and means to compromise the goal or to cause us to tarry or lose sight of the goal.  The goal is the star appearing, the star of Aquarius that has appeared over the Sun of my birth.  O beloved ones, the true star is the herald of the coming of the devotee, the Mighty I AM Presence of each one.  Remember your star!…
  You are eternal here and now. This place is your eternal abode, and I speak not of finite coordinates but of this place as the point of the eye of the Mind of God—the seat of your consciousness.  Find that seat now.  Feel it in the base of the brain and in the spine. Feel it in your heart!  Feel it in your soul!  Feel it in all of your being! That which you feel is God.  It is God, I tell you!  It is not some combination of physical senses.  Nay! That awareness of God in yourself is something above and beyond the form, yet it registers on the form….
But as it always is, the more vast the compendium of knowledge the greater the requirement of the teacher to organize. …
  You see, beloved ones, the tests are flying full and sure. We want you to experience the sense of mastery, of dominion, the enormous pleasure of having finished a day and dealt with that force, that driving force of irritation, and conquered and risen above every foible of the senses directed against your heart….
  Remember that anything that seeks to taunt you from the seat of the Buddha in the secret chamber of the heart must be noted as the enemy--not the person necessarily, for it is often a loved one, but the force attempting to use that one….Often it is a matter of stance.  How do you hold yourself?  Are you in readiness for the next delivery of God or thrust of the sinister force, or are you, as they say these days “laid-back”? …
  Whenever there is agreement in a principle of God a nucleus is formed--a bond of love. And that bond of love actually begins to consume the area of disagreement and error which may be in the mind of your friend or may be in your own mind, for we ourselves must see our own misconceptions, n’est-ce pas?  Perhaps you have noticed on a number of occasions that by your words and actions you may have caused some great grief and burden….Beloved ones, assume that those who come to you are injured and maimed and scarred, for they are. They have been in many battles of life. If you find them ornery or thick-skinned, this is a defense mechanism they have set up for a very deep hurt….
  Much of the cause of your failure of many tests is that you have not stopped to rid yourself of the human habit to express that aggravation, that arrogance--all coming from the need of the carnal mind to assert itself. It is not real! It has no power to dominate your personality! I speak directly to you, and all of you know whereof I speak!…Each and every time you begin to conceive of sin, an act of sin, you lose the protection of the entire Spirit of the Great White Brotherhood. …
  Beloved ones, if you remove yourselves from time and space and always find the center of the cross, you will dwell forevermore in the house of the Lord, the secret chamber of the heart, the sacred heart of Jesus whose heart I have made my own, imploring that Christ and therefore intensifying the purple fiery heart in his honor.  In that heart there is no desire for hashish, there is no desire for heroin….Fear is what binds you to the alternative path and method. …Cease then, cease from toying with the idea of unreality! Cease from the idea that you have ever been enslaved. The slaves of death must live in a consciousness of death!…Thus the only place where the consciousness of death and the astral plane can be canceled out is in the point of the will of the chela in this octave!…
  The higher helps the lower. As you accept help in humility, you can extend help. If you do not receive from the one above you, you cannot give to the one below you whose progress is utterly stopped because you yourself have stopped….
  One day the world must always turn against the living Christ.  And I do not think that any among you would consciously turn down the light of your Christ consciousness to be accepted by men, yet some of you do this unconsciously to avoid the challenge or the hurt or the public criticism.  Beloved ones, you can only go so far with this little game as you fit yourself in and out of society’s cliques….

  The “sorrowful way” comes only to the one who has not surrendered.  As soon as you surrender you are free--that is the key.  This is my crash course in passing every test.    
     
                             -Saint Germain:  7-6-1984 at Royal Teton Ranch, MT 
                                        via Messenger Elizabeth Clare Prophet