Wednesday, January 22, 2020

runaway big pharma


Billions of taxpayer dollars go into the creation and marketing16 of new drugs.  The Los Angeles Times reports that, “Since the 1930s, the National Institutes of Health has invested close to $90017 billion in the basic and applied research that formed both the pharmaceutical and biotechnology sectors.” Despite taxpayers’ crucial investment, U.S. consumers are increasingly paying more for their prescription drugs.
A 2018 study18 on the National Institute of Health’s (NIH) financial contributions to new drug approvals found that the agency “contributed to published research associated with every one of the 210 new drugs approved by the Food and Drug Administration from 2010–2016.” More than $100 billion in NIH funding went toward research that contributed directly or indirectly to the 210 drugs approved during that six-year period.  The NIH Research Project Grant (R01)19—which supports health-related research—was by far the most common kind of grant used to fund the science that supported the new drugs.  In all, NIH gave out nearly 118,00020 R01 grants related to those drugs from 2010 to 2016.  https://www.americanprogress.org/issues/democracy/reports/2019/08/30/473911/big-pharma-reaps-profits-hurting-everyday-americans/
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One in every five drugs FDA approved ends up causing serious harm.  https://pnhp.org/news/institutional-corruption-of-pharmaceuticals/
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In 2015, for instance, the 20 largest drug companies made a collective $124 billion in profits.  All the industry needs to protect those sums is the continued cooperation of Congress. https://www.nakedcapitalism.com/2017/06/whats-cost-keeping-pharma-stooge-senators-like-patty-murray-office.html
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Top Lobbying Clients, 2019
Client/ParentTotal
Pharmaceutical Research & Manufacturers of America $22,772,000
Biotechnology Innovation Organization $9,090,000
Pfizer Inc $8,700,000
Amgen Inc $8,540,000
Roche Holdings $8,355,000

2019-2020

ContributorAmount
Pfizer Inc  $725,442
DE Shaw Research  $723,947
Amgen Inc  $582,018
Eli Lilly & Co  $563,944
Roche Holdings  $486,126
AmerisourceBergen Corp  $439,353
Abbott Laboratories  $435,740
Abbvie Inc  $422,281
Johnson & Johnson  $380,397
Merck & Co  $374,175
North American Rescue Products  $313,900
AstraZeneca PLC  $274,201
Nephron Pharmaceuticals  $257,049
Novartis AG  $251,251
Vital Pharmaceuticals  $250,000
Medtronic Inc  $234,047
Masimo Corp  $228,515
GlaxoSmithKline  $209,936
Sanofi US  $206,219
Allergan plc  $202,626

Contributions to:
Democrats   
Republicans   
Liberal Groups 
Conservative Groups   
Nonpartisan 
                              Top Recipients, 2019-2020
CandidateOfficeAmount
Buttigieg, Pete (D) $253,792
McConnell, Mitch (R-KY)Senate $249,486
McCarthy, Kevin (R-CA)House $221,300
Sanders, Bernie (D)Senate $199,014
Tillis, Thom (R-NC)Senate $180,273 
   
https://www.opensecrets.org/industries/indus.php?ind=H04
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7-19-18   Big Pharma’s top eleven corporations generated net profits in just one decade from 2003 to 2012 of nearly three quarters of a trillion dollars – that’s just net profit alone. The net profit for 2012 amongst those top eleven amounted to $85 billion in just that one year. The majority of these largest pharmaceuticals are headquartered in the US – including the top four, Johnson & Johnson (#39 on Fortune 500 list), Pfizer (#51), Merck (#65) and Eli Lilly (#129) along with Abbott (#152) and Bristol Myers Squibb (#176). The healthcare research company IMS Health projects worldwide sales of Pharma drugs to exceed one trillion dollars by 2014….Big Pharma poured $2.7 billion into its lobbying interests from 1998 to 2013, 42% more than the second most “Gov. Corp.” bribe which happens to be its sister industry insurance.
  And it’s this unholy trinity of the medical establishment (personified by the American Medical Association), embedded insurance industry that wrote Obamacare into law and Big Pharma that makes the United States the most costly, broken, corrupt, destructive healthcare system in the entire world.  The structured system is designed and layered with built-in incentives at every tier to make and keep people sick, chronically dependent on their drugs for survival that merely mask and smother symptoms rather than cure or eradicate the root cause of disease….
  Even more alarming is the fact that death by medical error at near a quarter million people annually has become the third largest killer of US citizens behind heart disease and cancer. Other more recent studies have estimated upwards of up to 440,000 have died yearly from preventable mistakes at hospitals.  Blind obedience to Big Pharma and a conventional medical system too dependent on surgery and technology has inflicted more harm than good on the U.S. population.  https://www.globalresearch.ca/the-evils-of-big-pharma-exposed/5425382
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1-15-19    And herein lies the fundamental problem.  There are more doctors, more hospitals, more pharmaceutical drugs and medical procedures than ever before and yet we have not conquered nor made any significant progress in curing any major disease. Instead of making efforts to fund disease prevention and educate the public, prevention has been abandoned altogether.    https://prn.fm/corruption-science-leads-collapse-modern-civilization/
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9-27-19      There are three key provisions in the intellectual property rights chapter of the renegotiated NAFTA that would also be incorporated into any free-trade pact with India, all of which would prove to be a major coup for American pharmaceutical profiteering. First, patents would be granted for all innovations, including new methods, uses and processes of using a known product.  That alone would represent a major overhaul of the Indian Patents Act, which only provides patents if the innovations prove therapeutic efficacy.       https://readsludge.com/2019/09/27/trump-poised-to-give-big-pharma-a-big-present-in-india-trade-deal/
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Table 1. Top U.S. Drug Advertisement Expenditures (2016) 9

Drug/Maker
Advertisement
(in USD millions)
Purpose
Humira/AbbVie
$439
Anti-inflammatory
Lyrica/Pfizer
$392
Nerve pain management
Eliquis/Bristol-Myers Squibb
$296
Blood thinner
Xeljanz/Pfizer
$258
Anti-inflammatory
Opdivo/Bristol-Myers Squibb
$168
Cancer treatment
Chantix/Pfizer
$151
Smoking cessation
Cialis/Lilly
$150
Erectile dysfunction
Trulicity/Lilly
$142
Increase glucose (diabetes)
Prevnar/Pfizer
$142
Pneumonia vaccine
   The pharmaceutical industry spends hundreds of millions of dollars annually to market its products.  Direct-to-consumer prescription ads are the second-fastest growing ad category, competing with other top marketers stemming from automotive, fast food, insurance, and cable/wireless providers. 10, 11 Ad spending for television by pharmaceutical companies has more than doubled in the last four years, representing a 65% increase in this genre since 2012.    http://law.emory.edu/ecgar/content/volume-5/issue-2/essays/thieves-pharma-power-help-government-regulation.html.

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